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Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis

ABSTRACT: Spinal motoneurons are highly vulnerable in amyotrophic lateral sclerosis (ALS). Previous research using a standard animal model, the mutant superoxide dismutase-1 (SOD1) mouse, has revealed deficits in many cellular properties throughout its lifespan. The electrical properties underlying...

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Detalhes bibliográficos
Main Authors: Quinlan, K A, Schuster, J E, Fu, R, Siddique, T, Heckman, C J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098701/
https://ncbi.nlm.nih.gov/pubmed/21486770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.200659
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