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Progressive Changes in Synaptic Inputs to Motoneurons in Adult Sacral Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motoneurons. One potential mechanism is excitotoxicity. We studied the behaviors of spinal neurons using an in vitro preparation of the sacral cord from the G93A SOD1 mouse model of ALS. Measurements were conducted a...

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書誌詳細
主要な著者: Jiang, Mingchen, Schuster, Jenna E., Fu, Ronggen, Siddique, Teepu, Heckman, C. J.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000669/
https://ncbi.nlm.nih.gov/pubmed/19955354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0574-09.2009
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