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Progressive Changes in Synaptic Inputs to Motoneurons in Adult Sacral Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motoneurons. One potential mechanism is excitotoxicity. We studied the behaviors of spinal neurons using an in vitro preparation of the sacral cord from the G93A SOD1 mouse model of ALS. Measurements were conducted a...

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Detalhes bibliográficos
Main Authors: Jiang, Mingchen, Schuster, Jenna E., Fu, Ronggen, Siddique, Teepu, Heckman, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000669/
https://ncbi.nlm.nih.gov/pubmed/19955354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0574-09.2009
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