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Progressive Changes in Synaptic Inputs to Motoneurons in Adult Sacral Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motoneurons. One potential mechanism is excitotoxicity. We studied the behaviors of spinal neurons using an in vitro preparation of the sacral cord from the G93A SOD1 mouse model of ALS. Measurements were conducted a...

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Autores principales: Jiang, Mingchen, Schuster, Jenna E., Fu, Ronggen, Siddique, Teepu, Heckman, C. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000669/
https://ncbi.nlm.nih.gov/pubmed/19955354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0574-09.2009
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