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Identification of drivers for the metamorphic transition of HIV-1 reverse transcriptase

Recent structural characterizations of the p51 and p66 monomers has established an important starting point for understanding the maturation pathway of the HIV-1 reverse transcriptase p66/p51 heterodimer. This process requires a metamorphic transition of the polymerase domain leading to formation of...

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Foilsithe in:Biochem J
Main Authors: Zheng, Xunhai, Mueller, Geoffrey A., Kim, Kyungmin, Perera, Lalith, DeRose, Eugene F., London, Robert E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614878/
https://ncbi.nlm.nih.gov/pubmed/28811321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170480
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