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Protein-Mediated Antagonism between HIV Reverse Transcriptase Ligands Nevirapine and MgATP
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) play a central role in the treatment of AIDS, but their mechanisms of action are incompletely understood. The interaction of the NNRTI nevirapine (NVP) with HIV-1 reverse transcriptase (RT) is characterized by a preference for the open conforma...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686349/ https://ncbi.nlm.nih.gov/pubmed/23790378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.04.015 |
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