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Solution characterization of [methyl-(13)C]methionine HIV-1 reverse transcriptase by NMR spectroscopy

HIV reverse transcriptase (RT) is a primary target for drug intervention in the treatment of AIDS. Wereport the first solution NMR studies of [methyl-(13) C]methionine HIV-1 RT, aimed at better understanding the conformational and dynamic characteristics of RT, both in the presence and absence of th...

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Detaylı Bibliyografya
Asıl Yazarlar: Zheng, Xunhai, Mueller, Geoffrey A., DeRose, Eugene F., London, Robert E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807244/
https://ncbi.nlm.nih.gov/pubmed/19665484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.07.021
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