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Solution characterization of [methyl-(13)C]methionine HIV-1 reverse transcriptase by NMR spectroscopy
HIV reverse transcriptase (RT) is a primary target for drug intervention in the treatment of AIDS. Wereport the first solution NMR studies of [methyl-(13) C]methionine HIV-1 RT, aimed at better understanding the conformational and dynamic characteristics of RT, both in the presence and absence of th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807244/ https://ncbi.nlm.nih.gov/pubmed/19665484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.07.021 |
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