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Chemical Optimization Of Macrocyclic HIV-1 Inactivators For Improving Potency and Increasing the Structural Diversity at The Triazole Ring
HIV-1 entry inhibition remains an urgent need for AIDS drug discovery and development. We previously reported the discovery of cyclic peptide triazoles (cPTs) that retain the HIV-1 irreversible inactivation functions of the parent linear peptides (PTs) and have massively increased proteolytic resist...
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| Gepubliceerd in: | Org Biomol Chem |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5614861/ https://ncbi.nlm.nih.gov/pubmed/28770939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob01448a |
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