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Investigating cyclic nucleotide and cyclic dinucleotide binding to HCN channels by surface plasmon resonance
Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels control cardiac and neuronal rhythmicity. HCN channels contain cyclic nucleotide-binding domain (CNBD) in their C-terminal region linked to the pore-forming transmembrane segment with a C-linker. The C-linker couples the conforma...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5614581/ https://ncbi.nlm.nih.gov/pubmed/28950029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185359 |
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