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Focused Library Approach to Discover Discrete Dipeptide Bolaamphiphiles for siRNA Delivery

In this study, we report a new dipeptide functionalization strategy for developing new dendritic bolaamphiphile vectors for efficient siRNA transfection. A focused library of dipeptides was constructed using four amino acids: l-arginine, l-histidine, l-lysine, and l-tryptophan. The dipeptides were c...

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Detalhes bibliográficos
Publicado no:Biomacromolecules
Main Authors: Eldredge, Alexander C., Johnson, Mark E., Oldenhuis, Nathan J., Guan, Zhibin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612378/
https://ncbi.nlm.nih.gov/pubmed/27563833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.6b00635
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