In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery

Specific small interfering RNAs (siRNAs) designed to silence different oncogenic pathways can be used for cancer therapy. However, non-modified naked siRNAs have short half-lives in blood serum and encounter difficulties in crossing biological membranes due to their negative charge. These obstacles...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kim, Taejin, Afonin, Kirill A., Viard, Mathias, Koyfman, Alexey Y, Sparks, Selene, Heldman, Eliahu, Grinberg, Sarina, Linder, Charles, Blumenthal, Robert P, Shapiro, Bruce A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615820/
https://ncbi.nlm.nih.gov/pubmed/23511334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados