In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery

Specific small interfering RNAs (siRNAs) designed to silence different oncogenic pathways can be used for cancer therapy. However, non-modified naked siRNAs have short half-lives in blood serum and encounter difficulties in crossing biological membranes due to their negative charge. These obstacles...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, Taejin, Afonin, Kirill A., Viard, Mathias, Koyfman, Alexey Y, Sparks, Selene, Heldman, Eliahu, Grinberg, Sarina, Linder, Charles, Blumenthal, Robert P, Shapiro, Bruce A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2013
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615820/
https://ncbi.nlm.nih.gov/pubmed/23511334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.5
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia