Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However, the delivery of naked siRNAs is challenging becaus...

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Библиографические подробности
Опубликовано в: :Mol Ther Nucleic Acids
Главные авторы: Kim, Taejin, Viard, Mathias, Afonin, Kirill A., Gupta, Kshitij, Popov, Mary, Salotti, Jacqueline, Johnson, Peter F., Linder, Charles, Heldman, Eliahu, Shapiro, Bruce A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090283/
https://ncbi.nlm.nih.gov/pubmed/32200271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.02.011
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