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Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However, the delivery of naked siRNAs is challenging becaus...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Kim, Taejin, Viard, Mathias, Afonin, Kirill A., Gupta, Kshitij, Popov, Mary, Salotti, Jacqueline, Johnson, Peter F., Linder, Charles, Heldman, Eliahu, Shapiro, Bruce A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090283/
https://ncbi.nlm.nih.gov/pubmed/32200271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.02.011
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