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Bolaamphiphiles as Carriers for siRNA Delivery: From Chemical Syntheses to Practical Applications

In this study we have investigated a new class of cationic lipids – “bolaamphiphiles” or “bolas” for their ability to efficiently deliver small interfering RNAs (siRNAs) to cancer cells. The bolas of this study consist of a hydrophobic chain with one or more positively charged head groups at each en...

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Dades bibliogràfiques
Publicat a:J Control Release
Autors principals: Gupta, Kshitij, Afonin, Kirill A., Viard, Mathias, Herrero, Virginia, Kasprzak, Wojciech, Kagiampakis, Ioannis, Kim, Taejin, Koyfman, Alexey Y., Puri, Anu, Stepler, Marissa, Sappe, Alison, KewalRamani, Vineet N., Grinberg, Sarina, Linder, Charles, Heldman, Eliahu, Blumenthal, Robert, Shapiro, Bruce A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699870/
https://ncbi.nlm.nih.gov/pubmed/26151705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.06.041
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