Nrdp1 Increases Ischemia Induced Primary Rat Cerebral Cortical Neurons and Pheochromocytoma Cells Apoptosis Via Downregulation of HIF-1α Protein

Neuregulin receptor degradation protein-1 (Nrdp1) is an E3 ubiquitin ligase that targets proteins for degradation and regulates cell growth, apoptosis and oxidative stress in various cell types. We have previously shown that Nrdp1 is implicated in ischemic cardiomyocyte death. In this study, we inve...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Zhang, Yuan, Yang, Ke, Wang, Ting, Li, Weiping, Jin, Xinchun, Liu, Wenlan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611384/
https://ncbi.nlm.nih.gov/pubmed/28979191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00293
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