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Nrdp1 Increases Ischemia Induced Primary Rat Cerebral Cortical Neurons and Pheochromocytoma Cells Apoptosis Via Downregulation of HIF-1α Protein

Neuregulin receptor degradation protein-1 (Nrdp1) is an E3 ubiquitin ligase that targets proteins for degradation and regulates cell growth, apoptosis and oxidative stress in various cell types. We have previously shown that Nrdp1 is implicated in ischemic cardiomyocyte death. In this study, we inve...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Zhang, Yuan, Yang, Ke, Wang, Ting, Li, Weiping, Jin, Xinchun, Liu, Wenlan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611384/
https://ncbi.nlm.nih.gov/pubmed/28979191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00293
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