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Multifarious Functions of the Fragile X Mental Retardation Protein
Fragile X syndrome (FXS), a heritable intellectual and autism spectrum disorder, results from loss of Fragile X Mental Retardation Protein (FMRP). This neurodevelopmental disease state exhibits neural circuit hyperconnectivity and hyperexcitability. Canonically, FMRP functions as an mRNA-binding tra...
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| Publicado en: | Trends Genet |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610095/ https://ncbi.nlm.nih.gov/pubmed/28826631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2017.07.008 |
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