Preclinical validation of a single-treatment infusion modality that can eradicate extremity melanomas

Isolated limb perfusion (ILP) with the chemotherapeutic agent melphalan is an effective treatment option for extremity in-transit melanoma, but is toxic and technically challenging to deliver locoregionally. CBL0137 is an experimental clinical drug with broad anticancer activity in animal models, ow...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kim, Minhyung, Neznanov, Nickolay, Wilfong, Chandler D., Fleyshman, Daria I., Purmal, Andrei, Haderski, Gary, Stanhope-Baker, Patricia, Burkhart, Catherine A., Gurova, Katerina V., Gudkov, Andrei V., Skitzki, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609527/
https://ncbi.nlm.nih.gov/pubmed/27680682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2764
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