Smad7-overexpressing rat BMSCs inhibit the fibrosis of hepatic stellate cells by regulating the TGF-β1/Smad signaling pathway

Mesenchymal stem cells (MSCs) are able to differentiate into hepatocytes, promote the regeneration of hepatic cells and inhibit the progression of hepatic fibrosis. Transforming growth factor (TGF)-β1 is one of the key factors in the development of liver fibrosis, which also promotes extracellular m...

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Published in:Exp Ther Med
Main Authors: Wu, Shi-Pin, Yang, Zhi, Li, Fu-Rong, Liu, Xiao-Di, Chen, Hong-Tao, Su, Dong-Na
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609222/
https://ncbi.nlm.nih.gov/pubmed/28962196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4836
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