Rebalancing TGF‐β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis

BACKGROUND: Liver fibrosis and fibrosis‐related hepatocarcinogenesis are a rising cause for morbidity and death worldwide. Although transforming growth factor‐β (TGF‐β) is a critical mediator of chronic liver fibrosis, targeting TGF‐β isoforms and receptors lead to unacceptable side effect. This stu...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Yang, Yang, Sun, Mayu, Li, Weida, Liu, Chaobao, Jiang, Zheshun, Gu, Pengfei, Li, Jingquan, Wang, Wei, You, Rongli, Ba, Qian, Li, Xiaoguang, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255064/
https://ncbi.nlm.nih.gov/pubmed/34323416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.410
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