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Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors

Synthetic receptors provide a powerful experimental tool for generation of designer cells capable of monitoring the environment, sensing specific input signals, and executing diverse custom response programs. To advance the promise of cellular engineering, we have developed a class of chimeric recep...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Baeumler, Toni A., Ahmed, Ahmed Ashour, Fulga, Tudor A.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608971/
https://ncbi.nlm.nih.gov/pubmed/28903044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.044
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