Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function

Targeting protein-protein interaction (PPI) is rapidly becoming an attractive alternative for drug development. While drug development commonly involves inhibiting a PPI, in this study, we show that stabilizing PPI may also be therapeutically beneficial. Junctional proteins Neph1 and ZO-1 and their...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sagar, Amin, Arif, Ehtesham, Solanki, Ashish Kumar, Srivastava, Pankaj, Janech, Michael G., Kim, Seok-Hyung, Lipschutz, Joshua H., Kwon, Sang-Ho, Ashish, Nihalani, Deepak
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608913/
https://ncbi.nlm.nih.gov/pubmed/28935902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12134-8
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker