Slit Diaphragm Protein Neph1 and Its Signaling: A NOVEL THERAPEUTIC TARGET FOR PROTECTION OF PODOCYTES AGAINST GLOMERULAR INJURY

Podocytes are specialized epithelial cells that are critical components of the glomerular filtration barrier, and their dysfunction leads to proteinuria and renal failure. Therefore, preserving podocyte function is therapeutically significant. In this study, we identified Neph1 signaling as a therap...

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Detalhes bibliográficos
Main Authors: Arif, Ehtesham, Rathore, Yogendra S., Kumari, Babita, Ashish, Fnu, Wong, Hetty N., Holzman, Lawrence B., Nihalani, Deepak
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975002/
https://ncbi.nlm.nih.gov/pubmed/24554715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505743
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