Slit Diaphragm Protein Neph1 and Its Signaling: A NOVEL THERAPEUTIC TARGET FOR PROTECTION OF PODOCYTES AGAINST GLOMERULAR INJURY

Podocytes are specialized epithelial cells that are critical components of the glomerular filtration barrier, and their dysfunction leads to proteinuria and renal failure. Therefore, preserving podocyte function is therapeutically significant. In this study, we identified Neph1 signaling as a therap...

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Autori principali: Arif, Ehtesham, Rathore, Yogendra S., Kumari, Babita, Ashish, Fnu, Wong, Hetty N., Holzman, Lawrence B., Nihalani, Deepak
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975002/
https://ncbi.nlm.nih.gov/pubmed/24554715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505743
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