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Slit Diaphragm Protein Neph1 and Its Signaling: A NOVEL THERAPEUTIC TARGET FOR PROTECTION OF PODOCYTES AGAINST GLOMERULAR INJURY

Podocytes are specialized epithelial cells that are critical components of the glomerular filtration barrier, and their dysfunction leads to proteinuria and renal failure. Therefore, preserving podocyte function is therapeutically significant. In this study, we identified Neph1 signaling as a therap...

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Main Authors: Arif, Ehtesham, Rathore, Yogendra S., Kumari, Babita, Ashish, Fnu, Wong, Hetty N., Holzman, Lawrence B., Nihalani, Deepak
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975002/
https://ncbi.nlm.nih.gov/pubmed/24554715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505743
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