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Ischemic Injury to Kidney Induces Glomerular Podocyte Effacement and Dissociation of Slit Diaphragm Proteins Neph1 and ZO-1

Glomerular injury is often characterized by the effacement of podocytes, loss of slit diaphragms, and proteinuria. Renal ischemia or the loss of blood flow to the kidneys has been widely associated with tubular and endothelial injury but rarely has been shown to induce podocyte damage and disruption...

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Main Authors: Wagner, Mark C., Rhodes, George, Wang, Exing, Pruthi, Vikas, Arif, Ehtesham, Saleem, Moin A., Wean, Sarah E., Garg, Puneet, Verma, Rakesh, Holzman, Lawrence B., Gattone, Vince, Molitoris, Bruce A., Nihalani, Deepak
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602882/
https://ncbi.nlm.nih.gov/pubmed/18922801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805507200
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