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Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability

Neph1-deficient mice develop nephrotic syndrome at birth, indicating the importance of this protein in the development of a normal glomerular filtration barrier. While the precise subcellular localization of Neph1 remains unknown, its relationship with other components of the glomerular filtration b...

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Main Authors: Liu, Gang, Kaw, Beenu, Kurfis, Jayson, Rahmanuddin, Syed, Kanwar, Yashpal S., Chugh, Sumant S.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC164293/
https://ncbi.nlm.nih.gov/pubmed/12865409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318242
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