Impairment of human neural crest cell migration by prolonged exposure to interferon-beta

Human cell-based toxicological assays have been used successfully to detect known toxicants, and to distinguish them from negative controls. However, there is at present little experience on how to deal with hits from screens of compounds with yet unknown hazard. As a case study to this issue, we ch...

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Bibliographic Details
Published in:Arch Toxicol
Main Authors: Pallocca, Giorgia, Nyffeler, Johanna, Dolde, Xenia, Grinberg, Marianna, Gstraunthaler, Gerhard, Waldmann, Tanja, Rahnenführer, Jörg, Sachinidis, Agapios, Leist, Marcel
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2017
Subjects:
In Vitro Systems
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608792/
https://ncbi.nlm.nih.gov/pubmed/28365849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-1966-1
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