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Impairment of human neural crest cell migration by prolonged exposure to interferon-beta

Human cell-based toxicological assays have been used successfully to detect known toxicants, and to distinguish them from negative controls. However, there is at present little experience on how to deal with hits from screens of compounds with yet unknown hazard. As a case study to this issue, we ch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Arch Toxicol
Hauptverfasser: Pallocca, Giorgia, Nyffeler, Johanna, Dolde, Xenia, Grinberg, Marianna, Gstraunthaler, Gerhard, Waldmann, Tanja, Rahnenführer, Jörg, Sachinidis, Agapios, Leist, Marcel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608792/
https://ncbi.nlm.nih.gov/pubmed/28365849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-1966-1
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