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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

G-Protein-Coupled Receptors (GPCRs) are a large family of transmembrane receptors that play critical roles in normal cellular physiology and constitute a major pharmacological target for multiple indications, including analgesia, blood pressure regulation, and the treatment of psychiatric disease. U...

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Publicado en:J Vis Exp
Main Authors: Vasavda, Chirag, Zaccor, Nicholas W., Scherer, Paul C., Sumner, Charlotte J., Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608332/
https://ncbi.nlm.nih.gov/pubmed/28654029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55561
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