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IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination

Anabolic metabolism in lymphocytes promotes plasmablast and cytotoxic T cell differentiation at the expense of self-renewal. Heightened expression and function of the transcription factor IFN regulatory factor 4 (IRF4) accompany enhanced anabolic induction and full commitment to functional different...

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Detalhes bibliográficos
Publicado no:Immunohorizons
Main Authors: Kratchmarov, Radomir, Nish, Simone A., Lin, Wen-Hsuan W., Adams, William C., Chen, Yen-Hua, Yen, Bonnie, Rothman, Nyanza J., Klein, Ulf, Reiner, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608100/
https://ncbi.nlm.nih.gov/pubmed/28944344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1700012
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