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Caveolin-1-dependent BCR nanoscale organization regulates B cell tolerance
Caveolin-1 (Cav1) regulates plasma membrane nano-organization and compartmentalization. Here, we demonstrate that Cav1 controlled the distribution of immunoglobulin M (IgM)- and IgD- B cell antigen receptor (BCR) nanoclusters on the surface of B cells. In mature B cells, the IgM-BCR gained access to...
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Publicado no: | Nat Immunol |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608079/ https://ncbi.nlm.nih.gov/pubmed/28805811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3813 |
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