Biomechanical remodeling of the microenvironment by stromal Caveolin-1 favors tumor invasion and metastasis

Mechanotransduction, a key determinant of tissue homeostasis and tumor progression, is driven by intercellular adhesions, cell contractility and forces generated with the microenvironment, dependent on extracellular matrix composition, organization and compliance. Caveolin-1 (Cav1) favors cell elong...

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Autores principales: Goetz, Jacky G., Minguet, Susana, Navarro-Lérida, Inmaculada, Lazcano, Juan José, Samaniego, Rafael, Calvo, Enrique, Tello, Marta, Osteso-Ibáñez, Teresa, Pellinen, Teijo, Echarri, Asier, Cerezo, Ana, Klein-Szanto, Andres J.P., Garcia, Ricardo, Keely, Patricia J., Sánchez-Mateos, Paloma, Cukierman, Edna, Del Pozo, Miguel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244213/
https://ncbi.nlm.nih.gov/pubmed/21729786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.05.040
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