Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial–mesenchymal transition and fibrosis during peritoneal dialysis

Peritoneal dialysis (PD) is a form of renal replacement therapy whose repeated use can alter dialytic function through induction of epithelial–mesenchymal transition (EMT) and fibrosis, eventually leading to PD discontinuation. The peritoneum from Cav1(−/−) mice showed increased EMT, thickness, and...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Strippoli, Raffaele, Loureiro, Jesús, Moreno, Vanessa, Benedicto, Ignacio, Pérez Lozano, María Luisa, Barreiro, Olga, Pellinen, Teijo, Minguet, Susana, Foronda, Miguel, Osteso, Maria Teresa, Calvo, Enrique, Vázquez, Jesús, López Cabrera, Manuel, del Pozo, Miguel Angel
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309670/
https://ncbi.nlm.nih.gov/pubmed/25550395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404127
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