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The FcμR Limits Tonic BCR Signaling by Regulating IgM-BCR Expression
The IgM Fc receptor (FcμR), originally cloned as “Fas-apoptosis inhibitory molecule (FAIM3/TOSO)” can function as a cell surface receptor for secreted IgM on a variety of cell types. We report that FcμR also is expressed in the trans-Golgi network of developing B cells, where it constrains IgM- but...
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Publicado no: | Nat Immunol |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5310993/ https://ncbi.nlm.nih.gov/pubmed/28135254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3677 |
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