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The FcμR Limits Tonic BCR Signaling by Regulating IgM-BCR Expression
The IgM Fc receptor (FcμR), originally cloned as “Fas-apoptosis inhibitory molecule (FAIM3/TOSO)” can function as a cell surface receptor for secreted IgM on a variety of cell types. We report that FcμR also is expressed in the trans-Golgi network of developing B cells, where it constrains IgM- but...
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| 出版年: | Nat Immunol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5310993/ https://ncbi.nlm.nih.gov/pubmed/28135254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3677 |
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