Expression of Exogenous Cytokine in Patient-derived Xenografts via Injection with a Cytokine-transduced Stromal Cell Line

Patient-derived xenograft (PDX) mice are produced by transplanting human cells into immune deficient mice. These models are an important tool for studying the mechanisms of normal and malignant hematopoiesis and are the gold standard for identifying effective chemotherapies for many malignancies. PD...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Coats, Jacqueline S., Baez, Ineavely, Stoian, Cornelia, Milford, Terry-Ann M., Zhang, Xiaobing, Francis, Olivia L., Su, Ruijun, Payne, Kimberly J.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607929/
https://ncbi.nlm.nih.gov/pubmed/28518123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55384
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