A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis

Thymic stromal lymphopoietin (TSLP) stimulates in vitro proliferation of human fetal B-cell precursors. However, its in vivo role during normal human B lymphopoiesis is unknown. Genetic alterations that cause overexpression of its receptor component, cytokine receptor-like factor 2 (CRLF2), lead to...

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Publicado no:Haematologica
Main Authors: Francis, Olivia L., Milford, Terry-Ann M., Martinez, Shannalee R., Baez, Ineavely, Coats, Jacqueline S., Mayagoitia, Karina, Concepcion, Katherine R., Ginelli, Elizabeth, Beldiman, Cornelia, Benitez, Abigail, Weldon, Abby J., Arogyaswamy, Keshav, Shiraz, Parveen, Fisher, Ross, Morris, Christopher L., Zhang, Xiao-Bing, Filippov, Valeri, Van Handel, Ben, Ge, Zheng, Song, Chunhua, Dovat, Sinisa, Su, Ruijun Jeanna, Payne, Kimberly J.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004401/
https://ncbi.nlm.nih.gov/pubmed/26611474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.125336
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