A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis

Thymic stromal lymphopoietin (TSLP) stimulates in vitro proliferation of human fetal B-cell precursors. However, its in vivo role during normal human B lymphopoiesis is unknown. Genetic alterations that cause overexpression of its receptor component, cytokine receptor-like factor 2 (CRLF2), lead to...

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Udgivet i:Haematologica
Main Authors: Francis, Olivia L., Milford, Terry-Ann M., Martinez, Shannalee R., Baez, Ineavely, Coats, Jacqueline S., Mayagoitia, Karina, Concepcion, Katherine R., Ginelli, Elizabeth, Beldiman, Cornelia, Benitez, Abigail, Weldon, Abby J., Arogyaswamy, Keshav, Shiraz, Parveen, Fisher, Ross, Morris, Christopher L., Zhang, Xiao-Bing, Filippov, Valeri, Van Handel, Ben, Ge, Zheng, Song, Chunhua, Dovat, Sinisa, Su, Ruijun Jeanna, Payne, Kimberly J.
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004401/
https://ncbi.nlm.nih.gov/pubmed/26611474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.125336
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