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Fine-tuning patient-derived xenograft models for precision medicine approaches in leukemia
Many leukemias are characterized by well-known mutations that drive oncogenesis. Mice engineered with these mutations provide a foundation for understanding leukemogenesis and identifying therapies. However, data from whole genome studies provide evidence that malignancies are characterized by multi...
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| Publicado no: | J Investig Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154753/ https://ncbi.nlm.nih.gov/pubmed/26912005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jim-2016-000076 |
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