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VISMapper: ultra-fast exhaustive cartography of viral insertion sites for gene therapy
BACKGROUND: The possibility of integrating viral vectors to become a persistent part of the host genome makes them a crucial element of clinical gene therapy. However, viral integration has associated risks, such as the unintentional activation of oncogenes that can result in cancer. Therefore, the...
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| Publicado en: | BMC Bioinformatics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607581/ https://ncbi.nlm.nih.gov/pubmed/28931371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1837-z |
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