Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development

Epigenetic regulation is required to ensure the precise spatial and temporal pattern of gene expression that is necessary for embryonic development. Although the roles of some epigenetic modifications in embryonic development have been investigated in depth, the role of methylation at lysine 79 (H3K...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ogoh, Honami, Yamagata, Kazutsune, Nakao, Tomomi, Sandell, Lisa L., Yamamoto, Ayaka, Yamashita, Aiko, Tanga, Naomi, Suzuki, Mai, Abe, Takaya, Kitabayashi, Issay, Watanabe, Toshio, Sakai, Daisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607342/
https://ncbi.nlm.nih.gov/pubmed/28931923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11745-5
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