Longitudinal analysis of colon crypt stem cell dynamics in sulindac treated Familial Adenomatous Polyposis patients

The non-steroidal anti-inflammatory drug sulindac decreases size and number of adenomas after 4-6 months of treatment for familial adenomatous polyposis (FAP) patients. However, the underlying mechanism remains unknown. As stem cells are thought to be the tumor precursor cells, visualizing their beh...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Ma, Huiying, Brosens, Lodewijk A. A., Elias, Sjoerd G., Morsink, Folkert H. M., Nijman, Isaac J., Hylind, Linda M., Montgomery, Elizabeth A., Offerhaus, G. Johan A., Giardiello, Francis M., de Leng, Wendy W. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607292/
https://ncbi.nlm.nih.gov/pubmed/28931879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11865-y
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