Longitudinal analysis of colon crypt stem cell dynamics in sulindac treated Familial Adenomatous Polyposis patients

The non-steroidal anti-inflammatory drug sulindac decreases size and number of adenomas after 4-6 months of treatment for familial adenomatous polyposis (FAP) patients. However, the underlying mechanism remains unknown. As stem cells are thought to be the tumor precursor cells, visualizing their beh...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Huiying, Brosens, Lodewijk A. A., Elias, Sjoerd G., Morsink, Folkert H. M., Nijman, Isaac J., Hylind, Linda M., Montgomery, Elizabeth A., Offerhaus, G. Johan A., Giardiello, Francis M., de Leng, Wendy W. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607292/
https://ncbi.nlm.nih.gov/pubmed/28931879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11865-y
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