Multiwell capillarity-based microfluidic device for the study of 3D tumour tissue-2D endothelium interactions and drug screening in co-culture models

The tumour microenvironment is very complex, and essential in tumour development and drug resistance. The endothelium is critical in the tumour microenvironment: it provides nutrients and oxygen to the tumour and is essential for systemic drug delivery. Therefore, we report a simple, user-friendly m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Virumbrales-Muñoz, María, Ayuso, José María, Olave, Marta, Monge, Rosa, de Miguel, Diego, Martínez-Lostao, Luis, Le Gac, Séverine, Doblare, Manuel, Ochoa, Ignacio, Fernandez, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607255/
https://ncbi.nlm.nih.gov/pubmed/28931839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12049-4
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