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Development and characterization of a microfluidic model of the tumour microenvironment

The physical microenvironment of tumours is characterized by heterotypic cell interactions and physiological gradients of nutrients, waste products and oxygen. This tumour microenvironment has a major impact on the biology of cancer cells and their response to chemotherapeutic agents. Despite this,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ayuso, Jose M., Virumbrales-Muñoz, María, Lacueva, Alodia, Lanuza, Pilar M., Checa-Chavarria, Elisa, Botella, Pablo, Fernández, Eduardo, Doblare, Manuel, Allison, Simon J., Phillips, Roger M., Pardo, Julián, Fernandez, Luis J., Ochoa, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086897/
https://ncbi.nlm.nih.gov/pubmed/27796335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36086
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