Enabling cell recovery from 3D cell culture microfluidic devices for tumour microenvironment biomarker profiling

The tumour microenvironment (TME) has recently drawn much attention due to its profound impact on tumour development, drug resistance and patient outcome. There is an increasing interest in new therapies that target the TME. Nonetheless, most established in vitro models fail to include essential cue...

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Pubblicato in:Sci Rep
Autori principali: Virumbrales-Muñoz, María, Ayuso, Jose M., Lacueva, Alodia, Randelovic, Teodora, Livingston, Megan K., Beebe, David J., Oliván, Sara, Pereboom, Desirée, Doblare, Manuel, Fernández, Luis, Ochoa, Ignacio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470149/
https://ncbi.nlm.nih.gov/pubmed/30996291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42529-8
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