Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events

BACKGROUND: Glioblastoma (GBM) is one of the most lethal tumor types. Hypercellular regions, named pseudopalisades, are characteristic in these tumors and have been hypothesized to be waves of migrating glioblastoma cells. These “waves” of cells are thought to be induced by oxygen and nutrient deple...

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Foilsithe in:Neuro Oncol
Main Authors: Ayuso, Jose M., Monge, Rosa, Martínez-González, Alicia, Virumbrales-Muñoz, María, Llamazares, Guillermo A., Berganzo, Javier, Hernández-Laín, Aurelio, Santolaria, Jorge, Doblaré, Manuel, Hubert, Christopher, Rich, Jeremy N., Sánchez-Gómez, Pilar, Pérez-García, Víctor M., Ochoa, Ignacio, Fernández, Luis J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2017
Ábhair:
Basic and Translational Investigations
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464359/
https://ncbi.nlm.nih.gov/pubmed/28062831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now230
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