Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events

BACKGROUND: Glioblastoma (GBM) is one of the most lethal tumor types. Hypercellular regions, named pseudopalisades, are characteristic in these tumors and have been hypothesized to be waves of migrating glioblastoma cells. These “waves” of cells are thought to be induced by oxygen and nutrient deple...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Ayuso, Jose M., Monge, Rosa, Martínez-González, Alicia, Virumbrales-Muñoz, María, Llamazares, Guillermo A., Berganzo, Javier, Hernández-Laín, Aurelio, Santolaria, Jorge, Doblaré, Manuel, Hubert, Christopher, Rich, Jeremy N., Sánchez-Gómez, Pilar, Pérez-García, Víctor M., Ochoa, Ignacio, Fernández, Luis J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464359/
https://ncbi.nlm.nih.gov/pubmed/28062831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now230
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