Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events

BACKGROUND: Glioblastoma (GBM) is one of the most lethal tumor types. Hypercellular regions, named pseudopalisades, are characteristic in these tumors and have been hypothesized to be waves of migrating glioblastoma cells. These “waves” of cells are thought to be induced by oxygen and nutrient deple...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ayuso, Jose M., Monge, Rosa, Martínez-González, Alicia, Virumbrales-Muñoz, María, Llamazares, Guillermo A., Berganzo, Javier, Hernández-Laín, Aurelio, Santolaria, Jorge, Doblaré, Manuel, Hubert, Christopher, Rich, Jeremy N., Sánchez-Gómez, Pilar, Pérez-García, Víctor M., Ochoa, Ignacio, Fernández, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464359/
https://ncbi.nlm.nih.gov/pubmed/28062831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now230
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