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Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners

In eukaryotes, several “hub” proteins integrate signals from different interacting partners that bind through intrinsically disordered regions. The 14-3-3 protein hub, which plays wide-ranging roles in cellular processes, has been linked to numerous human disorders and is a promising target for ther...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Sluchanko, Nikolai N., Tugaeva, Kristina V., Greive, Sandra J., Antson, Alfred A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607241/
https://ncbi.nlm.nih.gov/pubmed/28931924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12214-9
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