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Concatenation of 14-3-3 with partner phosphoproteins as a tool to study their interaction

Regulatory 14-3-3 proteins interact with a plethora of phosphorylated partner proteins, however 14-3-3 complexes feature intrinsically disordered regions and often a transient type of interactions making structural studies difficult. Here we engineer and examine a chimera of human 14-3-3 tethered to...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Tugaeva, Kristina V., Kalacheva, Daria I., Cooley, Richard B., Strelkov, Sergei V., Sluchanko, Nikolai N.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802120/
https://ncbi.nlm.nih.gov/pubmed/31628352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50941-3
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