Structural basis for the interaction of a human small heat shock protein with the 14-3-3 universal signaling regulator

By interacting with hundreds of protein partners, 14-3-3 proteins coordinate vital cellular processes. Phosphorylation of the small heat shock protein HSPB6 within its intrinsically disordered N-terminal domain activates its interaction with 14-3-3, ultimately triggering smooth muscle relaxation. Af...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Sluchanko, Nikolai N., Beelen, Steven, Kulikova, Alexandra A., Weeks, Stephen D., Antson, Alfred A., Gusev, Nikolai B., Strelkov, Sergei V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321513/
https://ncbi.nlm.nih.gov/pubmed/28089448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.12.005
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