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Structural basis for the interaction of a human small heat shock protein with the 14-3-3 universal signaling regulator
By interacting with hundreds of protein partners, 14-3-3 proteins coordinate vital cellular processes. Phosphorylation of the small heat shock protein HSPB6 within its intrinsically disordered N-terminal domain activates its interaction with 14-3-3, ultimately triggering smooth muscle relaxation. Af...
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| Опубликовано в: : | Structure |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321513/ https://ncbi.nlm.nih.gov/pubmed/28089448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.12.005 |
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