The Mechanism of SARS-CoV-2 Nucleocapsid Protein Recognition by the Human 14-3-3 Proteins

The coronavirus nucleocapsid protein (N) controls viral genome packaging and contains numerous phosphorylation sites located within unstructured regions. Binding of phosphorylated SARS-CoV N to the host 14-3-3 protein in the cytoplasm was reported to regulate nucleocytoplasmic N shuttling. All seven...

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Publicado no:J Mol Biol
Main Authors: Tugaeva, Kristina V., Hawkins, Dorothy E.D.P., Smith, Jake L.R., Bayfield, Oliver W., Ker, De-Sheng, Sysoev, Andrey A., Klychnikov, Oleg I., Antson, Alfred A., Sluchanko, Nikolai N.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863765/
https://ncbi.nlm.nih.gov/pubmed/33556408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166875
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